Nucleic Acids

2'-O-MOE-A(Bz)-3'-phosphoramidite inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation.

3-Cyanovinylcarbazole Phosphoramidite can be used to form DNA strands incorporating cyanovinylcarbazole components.

2'-Fluoro-5MeC (Bz)-3'-phosphoramidite is a purine nucleoside amidite analog that can be used to produce oligonucleotides.

2'-OMe-G(iBu)-3'-phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis.

2'-O-Propargyl G(iBu)-3'-phosphoramidite, containing propargyl and benzoyl groups, readily attaches to diverse biomolecules. Through click chemistry, its reactive propargyl unit conjugates with azide-linked compounds, enabling versatile molecular binding for conjugation.

2'-O-Propargyl A(Bz)-3'-phosphoramidite includes exceptional propargyl and benzoyl functionalities that allow it to easily bind to a wide range of biomolecules. The propargyl unit, utilizing click chemistry, reacts with azide molecules for conjugation purposes.

5'-O-DMTr-5-iodo-2'-dU-3'-CED is a synthetic nucleoside phosphoramidite utilized to integrate iodo-modified deoxyuridine within an oligonucleotide, either internally or at the 5' end.

N4-Bz-5'-O-DMTr-2'-OMe-cytidine-3'-CED-phosphoramidite is a phosphoramidite monomer containing a 2'-OMe group and a cytosine nucleoside capped by a benzoyl functional group.

5'-O-DMTr-2'-O-TBDMS-N 1 -methylpseudouridine 3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite is a TBDMS-protected phosphoramidite monomer eligible for special oligonucleotide synthesis.