Antibodies

Protein ubiquitination is a regulatory mechanism that controls protein:protein interactions, protein degradation, and spatial localization, which is mediated by chain specific poly ubiquitination and/or mono ubiquitination. Anti ubiquitin antibody, AUB01, is a mouse monoclonal antibody that is part of the Signal Seeker line. The hybridoma has been licensed by Cytoskeleton from Fred Hutchinson Cancer Research Center.The antibody was raised against full length bovine ubiquitin.  The antibody has been shown to recognize polyubiquitin and free ubiquitin. AUB01 is purified by Protein G affinity chromatography and is supplied as a lyophilized white powder.

Anti-Human/Mouse C3/C3b/iC3b (FITC) (Clone: 6C9) (mouse IgG1)-Trial Size

Anti-RFP (RABBIT) Antibody Min X Hu Ms and Rt Serum Proteins

Fluorescent proteins such as Discosoma Red Fluorescent Protein (DsRed) from the mushroom anemone Discosoma sp. or green fluorescent protein (GFP) from Aequorea victoria jellyfish are widely used in research practice. Fusion proteins with RFP and GFP commonly serve as marker for gene expression and protein localization. As DsRed and GFP share only 19% identity, therefore, in general, anti-GFP antibodies do not recognize DsRed protein and vice versa. Structurally, Discosoma red fluorescent protein is similar to Aequorea green fluorescent protein in terms of its overall fold (a β-can) and chromophore-formation chemistry. However, Discosoma red fluorescent protein undergoes an additional step in the chromophore maturation and obligates tetrameric structure. Rockland offers many controls, monoclonal, and polyclonal antibodies for RFP.

F(ab')2 Anti-Mouse IgG (H&L) Peroxidase Antibody generated in goat was generated by enzymatic cleavage and subsequent separation from the Fc fragment. Because of their smaller size, F(ab)2 fragments offer several advantages over intact antibodies for use in certain immunochemical techniques and experimental applications. F(ab)2 fragments penetrate tissue samples and show better antigen recognition and signal generation in IHC. F(ab)2 fragments lack the Fc region and therefore do not bind Fc receptors which effectively lowers background staining. F(ab')2 Antibody is ideal for investigators who routinely perform flow cytometry, immunohistochemistry or IHC and other immunoassays.

Neutralizing recombinant murine/human chimeric antibody recognizing the PD-L1/PD-L2 binding region of human PD-1. This antibody does not cross-react with mouse PD-1, but does cross-react with monkey (M. fascicularis) PD-1. It has not been tested with other species.

Neutralizing recombinant chimeric murine/human monoclonal antibody recognizing the extracellular domain of PD-L1 and blocking the binding of PD-L1 to PD-1. This antibody has been shown to cross-react with mouse PD-L1. No other species have been tested.