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Antibiotics & Metabolites

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    Results for Antibiotics & Metabolites ( 164 )

      • Hydroxy Itraconazole

        Ref: TQ0224
        Sizes: 5 mg, 10 mg, 2 mg
        From: DKK3,353.00

        Hydroxy Itraconazole (R-63373) is an active metabolite of Itraconazole which is an antifungal agent.

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      • PSI-6206 13C,d3

        Ref: T12571
        Sizes: 5 mg, 10 mg
        From: DKK12,690.00

        PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.

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      • Ketopioglitazone

        Ref: T20465
        Sizes: 1 mg, 5 mg, 10 mg
        From: DKK3,045.00

        Ketopioglitazone is an active metabolite of pioglitazone.

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      • Ticagrelor metabolite M5

        Ref: T21059
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg
        From: DKK720.00

        Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster and more consistent inhibition on ADP-receptors. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).

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      • Axitinib sulfoxide

        Ref: T21129
        Sizes: 5 mg, 25 mg, 10 mg
        From: DKK8,235.00

        Axitinib sulfoxide is a major metabolite of Axitinib, which is a VEGFR tyrosine kinase inhibitor and may be useful in cancer therapy.

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      • Omeprazole sulfide

        Ref: T2687
        Sizes: 100 mg, 50 mg, 1 mL, 200 mg
        From: DKK285.00

        Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.

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      • Mupirocin

        Ref: 10-1101
        Sizes: 100 mg, 20 mg
        From: DKK840.00

        Activity: Antibiotic . Function/Pharmacology: Mupirocin is a topical antibiotic/antibacterial.1 It inhibits isoleucyl-tRNA synthase. High level mupirocin resistance was found in 8.2% of Staphylococcus aureus and 15.6% of coagulase-negative staphylococci with high level resistance being more common in methicillin-sensitive S. aureus in comparison with methicillin-resistant S. aureus.2

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      • 24(S)-Hydroxycholesterol

        Ref: 10-1331
        Sizes: 1 mg, 5 mg
        From: DKK683.00

        Activity: Endogenous cholesterol metabolite . Function/Pharmacology: 24(S)-Hydroxycholesterol is an important cholesterol metabolite (cholesterol 24-hydroxylase) found in the brain.1 It is an endogenous agonist of the nuclear receptor LXR.2 It has been shown to induce cell death in neuroblastoma cells3, possibly via a necroptosis pathway4. 24(S)-Hydroxycholesterol has also been found to be a high affinity ligand for RORα and RORγ (Ki = 25 nM).5 24(S)-Hydroxycholesterol levels are elevated in the cerebral spinal fluids of patients with neurogenerative diseases suggesting possible clinical applications.6,7 It was also able to reduce Aβ production and increase ER-resident immature amyloid precursor protein (APP) levels in human neuroblastoma SH-Sy5Y cells and CHO cells via inhibition of intracellular amyloid precursor protein trafficking.7

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      • Thiostrepton

        Ref: 10-2108
        Sizes: 1 g, 5 g
        From: DKK893.00

        Activity: Antibiotic and FOXM1 inhibitor . Function/Pharmacology: Novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as the activity of initiation factor-1 (IF-2)1-2. Displays antitumor activity. Induces apoptosis and cell cycle arrest in various tumor cells via downregulation of FOXM1 expression3. Chemical Name: Fermentation product from Streptomyces azureus

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