Labelling

SPY7000-tubulin is a bright, far-red & non-toxic live cell microtubule stain based on SPY™ dyes series. Its optimized structure allows quick labeling of microtubules in live cells with high specificity and very low background. SPY650-tubulin stains microtubules in live cells without the need for genetic manipulation or overexpression of fluorescent proteins. Its absorbance and emission spectra are similar to Cy5. SPY650-tubulin enables multicolour imaging with SPY505, SPY555, SPY595, SPY700, GFP or m-cherry. SPY650-tubulin can be imaged with standard Cy5 filtersets. It can be used for widefield, confocal, SIM or STED imaging in living cells and tissue.

LysoTrack™ Red is a cell-permeable, non-fixable, red-fluorescent dye that selectively stains lysosomes in live cells. This dye has an excitation and emission maximum of 582/592 nm and can be efficiently excited using a TRITC filter. This probe is provided as 1 mM solution in DMSO.

PKmito Orange FX (also known as PKMO FX) is a bright, photostable, mitochondrial probe based on the PKmito™ dyes.

PKmem 560 is a bright, non-phototoxic & non-toxic plasma membrane probe based on the PKmem™ dyes developed by the lab of Zhixing Chen at Peking University. PKmem 560 labels the plasma membrane in live cells with very high specificity. The unique and unmatched feature of PKmem 560 is its extremely low phototoxicity, due to the presence of the intramolecular triplet quencher cyclooctatetraene (COT) group. It allows to perform long term live cell imaging of the plasma membrane without damaging the cells. PKmem 560 does not require any genetic manipulation, transfection or overexpression of fluorescent proteins. PKmem 560 enables multicolor imaging with SPY505, SPY595, SPY650, SPY700, SiR or GFP. PKmem 560 can be imaged with a standard TMR or Cy3 filterset. It can be used for widefield, confocal, SIM or STED imaging in living cells and tissue. Contains 1 vial of PKmem 560 (lyophilized).

PKmem 590 is a bright, non-phototoxic & non-toxic plasma membrane probe based on the PKmem™ dyes developed by the lab of Zhixing Chen at Peking University. PKmem 590 labels the plasma membrane in live cells with very high specificity. The unique and unmatched feature of PKmem 590 is its extremely low phototoxicity, due to the presence of the intramolecular triplet quencher cyclooctatetraene (COT) group. It allows to perform long term imaging the plasma membrane without damaging the cells. It is highly suited to image plasma membrane structure and dynamics by STED superresolution microscopy using a 775 nm depletion line. PKmem 590 does not require any genetic manipulation, transfection or overexpression of fluorescent proteins. PKmem 590 enables multicolor imaging with SPY505, SPY555, SPY620, SPY650, SPY700, SiR or GFP. It can be used for widefield, confocal, SIM or STED imaging in living cells and tissue. Contains 1 vial of PKmem 590 (lyophilized).

PKmem 640 is a bright, non-phototoxic & non-toxic plasma membrane probe based on the PKmem™ dyes developed by the lab of Zhixing Chen at Peking University1-3). PKmem 640 labels the plasma membrane in live cells with very high specificity. The unique and unmatched feature of PKmem 640 is its extremely low phototoxicity, due to the presence of the intramolecular triplet quencher cyclooctatetraene (COT) group. It allows to perform long term live cell imaging of the plasma membrane without damaging the cells. PKmem 640 does not require any genetic manipulation, transfection or overexpression of fluorescent proteins. PKmem 640 enables multicolor imaging with SPY505, SPY555, SPY595, SPY620 or GFP. PKmem 640 can be imaged with a standard Cy5 filterset. It can be used for widefield, confocal, SIM or STED imaging in living cells and tissue. Contains 1 vial of PKmem 640 (lyophilized).