Antibiotics & Metabolites

against mycobacteria

Aminoglycoside antibiotic

LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.

Antibiotic-5d is a synthetic antimicrobial compound. It exhibits moderate antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria, fungi and yeast.

N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.

Lurasidone metabolite 14326 hydrochloride, an active metabolite of the atypical antipsychotic Lurasidone, maintains its significant function in pharmacological efficacy.

Mebeverine alcohol [Mebeverine metabolite]: Mebeverine alcohol is a primary metabolite of the antispasmodic agent Mebeverine.

Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

Hydroxy Itraconazole (R-63373) is an active metabolite of Itraconazole which is an antifungal agent.