In recent years, much attention has been paid to the study of the senolytic drug. The mechanism of cellular senescence is complicated, so the changes are observed in multiple indicators such as oxygen consumption rate (OCR), mitochondrial membrane potential, energy production, and more…
In particular, OCR measurement which directly reflects mitochondrial activity, is useful as a method of characterizing the phenotype of senescent cells and evaluating the effects of cellular senescence on mitochondrial function.
Extracellular Oxygen Consumption Rate(OCR) Plate Assay Kit:
Disruption of intracellular nutrients, (such as glucose, fatty acids, amino acids) can lead to changes in cellular metabolism (such as mitochondrial basal respiration) and activity. It is also involved in the regulation of senescence, for example, cystine induces cellular senescence in melanoma. All of these nutrients play a crucial role in this natural cellular process, and monitoring their fluctuating levels can give you a more complete insight of this cellular process. Complete your senescence toolbox with the following assay kits.
Ref: SG03-10 - Size: 10 Assays
Ref: G270-10 - Size: 50 tests
Ref: G272-10 - Size: 50 tests
Ref: UP02-10 - Size: 1 set
Ref: UP05-10 - Size: 20 tests; Ref: UP05-12 - Size: 100 tests
Ref: UP07-10 - Size: 100 tests
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