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    Results for Chemicals & Small Molecules ( 82986 )

      • Ref: T63226
        Sizes: 1 mg, 5 mg, 10 mg
        From: €65.00

        Asciminib (ABL001) hydrochloride is a selective and potent mutant BCR-ABL1 inhibitor that inhibits Ba/F3 cell growth (IC50: 0.25 nM).

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      • Ref: T63227
        Sizes: 5 mg, 100 mg, 50 mg
        From: €1,101.00

        Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) is a soft steroid with a weak anti-inflammatory effect and a short duration of action that can be used to study several eye diseases and gastric ulcers.

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      • Ref: T63228
        Sizes: 1 mg, 100 mg, 50 mg
        From: €132.00

        Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR)-deficient cells, thereby contributing to apoptosis.Simmiparib has been used for study Parkinson's disease, Alzheimer's disease, breast cancer, and melanoma.

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      • Ref: T63229
        Sizes: 5 mg, 100 mg, 50 mg
        From: €1,101.00

        ITK inhibitor 6 is a selective and potent ITK inhibitor that acts on ITK (IC50: 4 nM), BTK (IC50: 133 nM), JAK3 (IC50: 320 nM), EGFR (IC50: 2360 nM), LCK (IC50: 155 nM). ITK inhibitor 6 inhibited the phosphorylation of PLCγ1 and ERK1/2 and showed anti-proliferative effect.

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      • Ref: T63230
        Sizes: 5 mg, 100 mg, 50 mg
        From: €1,101.00

        RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research (from patent WO2021093720A1, compound I-1).

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      • Ref: T63231
        Sizes: 5 mg, 100 mg, 50 mg
        From: €1,101.00

        LPA5 antagonist 1 is a selective and potent lysophosphatidic acid receptor 5 (LPA5) antagonist with an IC50 value of 32 nM. LPA5 antagonist 1 has high brain permeability and antinociceptive activity and can be used to study inflammatory and neuropathic pain.

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      • Ref: T63232
        Sizes: 5 mg, 100 mg, 50 mg
        From: €1,101.00

        Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.

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      • Ref: T63233
        Sizes: 5 mg, 100 mg, 50 mg
        From: €1,101.00

        Neuraminidase-IN-10 is a neuraminidase inhibitor that exhibits anti-influenza effects and is able to act on H1N1 (IC50: 2.6 nM), H5N1 (IC50: 5.1 nM) and H5N8 (IC50: 1.65 nM).

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      • Ref: T63234
        Sizes: 5 mg, 100 mg, 50 mg
        From: €1,101.00

        Factor XI-IN-1 is an inhibitor of factor XI activation (EC50: 25.14 nM).

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